Solid-phase microextraction, or SPME, is a sample preparation technique that involves the use of a fiber coated with an extracting phase, that can be a liquid (polymer) or a solid (sorbent), which extracts different kinds of analytes (including both volatile and non-volatile) from different kinds of media, that can be in liquid or gas phase. The q... Found on http://en.wikipedia.org/wiki/Solid-phase_microextraction